What are some common factors that prevent a file from being Print-Ready?

Common factors that prevent a layout file from being Print-Ready include…. Document sized improperly. Colors are set to RGB instead of CMYK. Spot colors are not properly defined. Not allowing ample margins (putting information or borders closer than 1/4” from any trimmed edge). Resolution not high enough (should be minimum 300 dpi at 100% size), bleeds not set up correctly (artwork should extend at least 1/8” past crop marks), crop Marks missing or incorrectly placed, missing fonts or images, poor contrast between the text and background, spelling, and grammar errors.